GS15081
Protein
Uniprot ID:P14719-2 (2-337aa)
Il1rl1, Ly84, St2, Ste2
Mammalian cell
Mus musculus (house mouse)
C-terminal FLAG-tagged；C-terminal His-tagged；
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-140℃.
For research use only
白細(xì)胞介素1受體樣1 (IL1RL1)是白細(xì)胞介素1受體家族的一員，包含3個(gè)ig樣c2型結(jié)構(gòu)域和1個(gè)TIR結(jié)構(gòu)域。它在腎、肺、胎盤、胃、骨骼肌、結(jié)腸和小腸中高度表達(dá)。IL1RL1是白細(xì)胞介素-33的受體，它的刺激招募MYD88, IRAK1, IRAK4和TRAF6，然后磷酸化MAPK3/ ERK1和/或MAPK1/ ERK2, MAPK14和MAPK8。IL1RL1可能參與輔助t細(xì)胞的功能?？扇苄訧L1RL1還作為Th2細(xì)胞因子產(chǎn)生的負(fù)調(diào)節(jié)因子，它直接涉及心臟病的進(jìn)展。
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